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This fifth edition of the most accessible introduction to MRI principles and applications from renowned teachers in the field provides an understandable yet comprehensive update. Accessible introductory guide from renowned teachers in the field Provides a concise yet thorough introduction for MRI focusing on fundamental physics, pulse sequences, and clinical applications without presenting advanced math Takes a practical approach, including up-to-date protocols, and supports technical concepts with thorough explanations and illustrations Highlights sections that are directly relevant to radiology board exams Presents new information on the latest scan techniques and applications including 3 Tesla whole body scanners, safety issues, and the nephrotoxic effects of gadolinium-based contrast media

Offering the latest information in magnetic nanoparticle (MNP) research, this book builds upon the success of the first volume and provides an updated and comprehensive review, from synthesis, characterization, and biofunctionalization to clinical applications of MNPs, including the diagnosis and treatment of cancers. The book captures some of emerging research area which was not available in the first volume. Good Manufacturing Practices and Commercialization of MNPs are also included. This volume, also written by some of the most qualified experts in the field, incorporates new developments in the literature, and continues to bridge the gaps between the different areas in this field.

Preceded by: Abdominal-pelvic MRI / Richard C. Semelka. 3rd ed. c2010.

Brain and Behavior Computing offers insights into the functions of the human brain. This book provides an emphasis on brain and behavior computing with different modalities available such as signal processing, image processing, data sciences, statistics further it includes fundamental, mathematical model, algorithms, case studies, and future research scopes. It further illustrates brain signal sources and how the brain signal can process, manipulate, and transform in different domains allowing researchers and professionals to extract information about the physiological condition of the brain. Emphasizes real challenges in brain signal processing for a variety of applications for analysis, classification, and clustering. Discusses data sciences and its applications in brain computing visualization. Covers all the most recent tools for analysing the brain and it’s working. Describes brain modeling and all possible machine learning methods and their uses. Augments the use of data mining and machine learning to brain computer interface (BCI) devices. Includes case studies and actual simulation examples. This book is aimed at researchers, professionals, and graduate students in image ...

This book explores various state-of-the-art aspects behind the statistical analysis of neuroimaging data. It examines the development of novel statistical approaches to model brain data. Designed for researchers in statistics, biostatistics, computer science, cognitive science, computer engineering, biomedical engineering, applied mathematics, physics, and radiology, the book can also be used as a textbook for graduate-level courses in statistics and biostatistics or as a self-study reference for Ph.D. students in statistics, biostatistics, psychology, neuroscience, and computer science.

Statistical Techniques for Neuroscientists introduces new and useful methods for data analysis involving simultaneous recording of neuron or large cluster (brain region) neuron activity. The statistical estimation and tests of hypotheses are based on the likelihood principle derived from stationary point processes and time series. Algorithms and software development are given in each chapter to reproduce the computer simulated results described therein. The book examines current statistical methods for solving emerging problems in neuroscience. These methods have been applied to data involving multichannel neural spike train, spike sorting, blind source separation, functional and effective neural connectivity, spatiotemporal modeling, and multimodal neuroimaging techniques. The author provides an overview of various methods being applied to specific research areas of neuroscience, emphasizing statistical principles and their software. The book includes examples and experimental data so that readers can understand the principles and master the methods. The first part of the book deals with the traditional multivariate time series analysis applied to the context of multichannel...

In the medical imaging field, clinicians and researchers are increasingly moving from the qualitative assessment of printed images to the quantitative evaluation of digital images since the quantitative techniques often improve diagnostic accuracy and complement clinical assessments by providing objective criteria. Despite this growing interest, the field lacks a comprehensive body of knowledge. Filling the need for a complete manual on these novel techniques, Quantifying Morphology and Physiology of the Human Body Using MRI presents a wide range of quantitative MRI techniques to study the morphology and physiology of the whole body, from the brain to musculoskeletal systems. Illustrating the growing importance of quantitative MRI, the book delivers an indispensable reference for readers who would like to explore in vivo MRI techniques to quantify changes in the morphology and physiology of tissues caused by various disease mechanisms. With internationally renowned experts sharing their insight on the latest developments, the book goes beyond conventional MRI contrast mechanisms to include new techniques that measure electromagnetic and mechanical properties of tissues. Each...

An important aspect of neuroscience is to characterize the underlying connectivity patterns of the human brain (i.e., human connectomics). Over the past few years, researchers have demonstrated that by combining a variety of different neuroimaging technologies (e.g., structural MRI, diffusion MRI and functional MRI) with sophisticated analytic strategies such as graph theory, it is possible to noninvasively map the patterns of structural and functional connectivity of human whole-brain networks. With these novel approaches, many studies have shown that human brain networks have nonrandom properties such as modularity, small-worldness and highly connected hubs. Importantly, these quantifiable network properties change with age, learning and disease. Moreover, there is growing evidence for behavioral and genetic correlates. Network analysis of neuroimaging data is opening up a new avenue of research into the understanding of the organizational principles of the brain that will be of interest for all basic scientists and clinical researchers. Such approaches are powerful but there are a number of challenging issues when extracting reliable brain networks from various imaging...

The first complete textbook and atlas of the vitally importanttechnique of bone age assessment utilizing MRI for children's handand wrist This latest volume in the growing Wiley Current Clinical Imagingseries is a must-have resource that collects, in a single volume,all that is currently known and applicable about the use ofmagnetic resonance imaging (MRI) for the assessment of boneage. Presented in two parts, Text-Atlas of Skeletal AgeDetermination: MRI of the Hand and Wrist in Children firstfocuses on the anatomic, social, and legal aspects of bone age,providing a concise overview of the use of bone age determinationin medical, legal, and social systems.??It then covers the clinicaluse and application of MRI in assessing bone age. The book offerscomplete chapter coverage on endocrinology, puberty, and disordersof pubertal development; bone marrow maturation in healthy anddiseased states; growth failure and pediatric inflammatory boweldisease; skeletal findings in neurometabolic disease, geneticdisease, and pediatric oncology patients; and much more. Text-Atlas of Skeletal Age Determination provides: A comprehensive review of the medical, legal, and socialaspects of bone age...

Editor Hersh Chandarana, MD and authors review Advanced MR Imaging in Clinical Practice. Articles will include: Current Status of Diffusion Weighted Imaging; Current Status of Perfusion Weighted Imaging; Non-gadolinium Enhanced MR Angiography; Pearls and Pitfalls of 3 T imaging; Implementing MR Neurography in Clinical Practice; Imaging around Hardware and Metal; Recent Advances in T1- and T2-Weighted Imaging of the Abdomen and Pelvis; Recent Advances in Neuro and Spine Imaging; Advances in MR Hardware and Software, and more!

Brain Mapping: A Comprehensive Reference offers foundational information for students and researchers across neuroscience. With over 300 articles and a media rich environment, this resource provides exhaustive coverage of the methods and systems involved in brain mapping, fully links the data to disease (presenting side by side maps of healthy and diseased brains for direct comparisons), and offers data sets and fully annotated color images. Each entry is built on a layered approach of the content – basic information for those new to the area and more detailed material for experienced readers. Edited and authored by the leading experts in the field, this work offers the most reputable, easily searchable content with cross referencing across articles, a one-stop reference for students, researchers and teaching faculty. Broad overview of neuroimaging concepts with applications across the neurosciences and biomedical research Fully annotated color images and videos for best comprehension of concepts Layered content for readers of different levels of expertise Easily searchable entries for quick access of reputable information Live reference links to ScienceDirect, Scopus and PubMed

Over the past several decades, much progress has been made in understanding the mechanisms of electrical activity in biological tissues and systems, and for developing non-invasive functional imaging technologies to aid clinical diagnosis of dysfunction in the human body. The book will provide full basic coverage of the fundamentals of modeling of electrical activity in various human organs, such as heart and brain. It will include details of bioelectromagnetic measurements and source imaging technologies, as well as biomedical applications. The book will review the latest trends in the field and comment on the future direction in this fast developing line of research.

Handbook of Medical Image Computing and Computer Assisted Intervention presents important advanced methods and state-of-the art research in medical image computing and computer assisted intervention, providing a comprehensive reference on current technical approaches and solutions, while also offering proven algorithms for a variety of essential medical imaging applications. This book is written primarily for university researchers, graduate students and professional practitioners (assuming an elementary level of linear algebra, probability and statistics, and signal processing) working on medical image computing and computer assisted intervention. Presents the key research challenges in medical image computing and computer-assisted intervention Written by leading authorities of the Medical Image Computing and Computer Assisted Intervention (MICCAI) Society Contains state-of-the-art technical approaches to key challenges Demonstrates proven algorithms for a whole range of essential medical imaging applications Includes source codes for use in a plug-and-play manner Embraces future directions in the fields of medical image computing and computer-assisted intervention

This volume presents the proceedings of the Brazilian Congress on Biomedical Engineering (CBEB 2018). The conference was organised by the Brazilian Society on Biomedical Engineering (SBEB) and held in Armação de Buzios, Rio de Janeiro, Brazil from 21-25 October, 2018. Topics of the proceedings include these 11 tracks: • Bioengineering • Biomaterials, Tissue Engineering and Artificial Organs • Biomechanics and Rehabilitation • Biomedical Devices and Instrumentation • Biomedical Robotics, Assistive Technologies and Health Informatics • Clinical Engineering and Health Technology Assessment • Metrology, Standardization, Testing and Quality in Health • Biomedical Signal and Image Processing • Neural Engineering • Special Topics • Systems and Technologies for Therapy and Diagnosis

This volume explores the revolutionary fMRI field from basic principles to state-of-the-art research. It covers a broad spectrum of topics, including the history of fMRI's development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI; fMRI of the visual system, auditory cortex, and sensorimotor system; genetic imaging using fMRI, multimodal neuroimaging, brain bioenergetics and function and molecular-level fMRI. Comprehensive and intuitively structured, this book engages the reader with a first-person account of the development and history of the fMRI field by the authors. The subsequent sections examine the physiological basis of fMRI, the basic principles of fMRI and its applications and the latest advances of the technology, ending with a discussion of fMRI’s future. fMRI: From Nuclear Spins to Brain Function, co-edited by leading and renowned fMRI researchers Kamil Ugurbil, Kamil Uludag and Lawrence Berliner, is an ideal resource for clinicians and researchers in the fields of neuroscience, psychology and MRI physics.

The popularity of magnetic resonance (MR) imaging in medicine is no mystery: it is non-invasive, it produces high quality structural and functional image data, and it is very versatile and flexible. Research into MR technology is advancing at a blistering pace, and modern engineers must keep up with the latest developments. This is only possible with a firm grounding in the basic principles of MR, and Advanced Image Processing in Magnetic Resonance Imaging solidly integrates this foundational knowledge with the latest advances in the field. Beginning with the basics of signal and image generation and reconstruction, the book covers in detail the signal processing techniques and algorithms, filtering techniques for MR images, quantitative analysis including image registration and integration of EEG and MEG techniques with MR, and MR spectroscopy techniques. The final section of the book explores functional MRI (fMRI) in detail, discussing fundamentals and advanced exploratory data analysis, Bayesian inference, and nonlinear analysis. Many of the results presented in the book are derived from the contributors' own work, imparting highly practical experience through experimental and...

Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur

This book constitutes the refereed proceedings of the 16th Scandinavian Conference on Image Analysis, SCIA 2011, held in Ystad, Sweden, in May 2011. The 74 revised full papers presented were carefully reviewed and selected from 140 submissions. The papers are organized in topical sections on multiple view geometry; segmentation; image analysis; categorization and classification; structure from motion and SLAM; medical and biomedical applications; 3D shape; medical imaging.

This volume contains the 137 papers accepted for presentation at the 15th European Conference on Artificial Intelligence (ECAI '02), which is organized by the European Co-ordination Committee on Artificial Intelligence.

Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson’s Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more. This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery. Written to provide a "hands-on" approach for neuroscience graduate students, as well as medical personnel from the fields of neurology and neurosurgery Includes preprocessing strategies (such as co-registration, normalization, lead...

It has been long assumed that following the resolution of acute injuries, traumatic brain injury represents a stable neural entity. However, there is growing evidence that a single moderate-severe brain injury may instead trigger an ongoing deteriorative process that commences sub-acutely, and occurs regardless of age. For scientists and clinicians, it is critical to examine this body of evidence and to explore its implications. Do the findings represent a neurodegenerative process or can they be alternatively explained? What are the neural, behavioural and functional characteristics of this progressive deterioration? Such information is needed to develop treatments to prevent or mitigate decline, and to inform the clinical care of brain injured patients. Research and clinical practice are influenced by the assumption that moderate-severe TBI is non-progressive, with few studies exploring treatments to prevent progression, and rehabilitation typically concentrated in the early stages of injury. Brain injuries can never be fully prevented. However, understanding that such progressive deterioration occurs opens a novel area of research - prevention of secondary decline - offering...

It is acknowledged that practice could induce rapid change or reorganization of the brain’s cellular or neural networks as well as behaviors. Notably, practice relevant to mental or physical approach attracted great attention in this decade. It highlights profound significance both for human evolvement and individual development. Specifically, acquiring fine motor skills is a crucial premise for human being to evolve to modern human by using tools in one side. In the other side, numerous evidences indicated that motor learning involved in limb and trunks promotes the development of individual brain in anatomy and functions. Hence, motor learning is also tightly associated with developmental plasticity. These studies on brain-mind-body practice illuminate a promising way in promoting human brain health. This editorial covers wide range of brain-mind-body practice forms to summarize recent new findings and development from behavioral, physiological, neurobiological and psychological science approaches. In this research topic, we addressed recent findings from theoretical as well as experimental perspective including contributions under the following three headings: 1) intervention ...

The improvement of exercise performance in sports not only involves the enhancement of physical strength, but also includes the development of psychological and cognitive functions. There is an increasing body of evidence to show that physical exercise is a powerful way to improve a number of aspects of cognition and brain function at the systemic and behavioral levels. Yet, several questions remain: What type of exercise program is optimal for improving cognitive functions? What are the real effects of certain innovative exercise protocols on the relationship between behavior and the brain? To what extent do ergogenic aids boost cognitive function? How efficient are neuromodulation techniques in relation to behavioral performance? The answers to these questions likely require multidisciplinary insights not only from physiologists and sports scientists, but also from neuroscientists and psychologists. The manuscripts published (16 research papers and one perspective article from various academic fields) in this Special Issue Book “Exercise: A Gate That Primes the Brain to Perform” bring together current knowledge and novel directions in human exercise-cognition research...

This unique, contemporary book is the successor edition of a ground-breaking, authoritative title devoted to the pathology and treatment of chiari malformations. Since an abundance of research and development has occurred after the publication of the Chiari Malformations this updated title meets the market need for a reference that reflects such advances in the field. Chiari Malformations, 2nd Edition is divided into nine sections. Opening sections feature chapters on general aspects, diagnostic features and clinical presentation. These are followed by sections on differential diagnosis, treatment and prognosis. Finally, the book closes with an extensive discussion on research, related pathologies and patient resources. Expertly written chapters are supplemented with numerous high-quality illustrations and images to aid in visual learning. An impressive, nuanced successor, Chiari Malformations, 2nd Edition, is an invaluable resource for neuroscientists and clinicians at all levels, as well as graduate students to specific research scientists studying this region.

" Sleep in Childhood Neurological Disorders addresses the myriad sleep-wake issues associated with neurological disturbances from the newborn period through adolescence. The editors and contributing authors are internationally recognized authorities who cover everything from sleep and ADHD, headaches, restless leg syndrome, parasomnias, hypersomnias, autism, brain tumors, epilepsy, traumatic brain injury, and other primary disorders to sleep co-morbidities, assessment, testing, interventions, pharmacology and more. The first book devoted to the growing field of pediatric neurosomnology, Sleep in Childhood Neurological Disorders is an invaluable text for clinicians looking for current information and practical guidance to successfully manage their pediatric sleep patients. Sleep in Childhood Neurological Disorders features Dedicated focus on neurologically-based sleep disorders in children Diagnostic tables, key points, clinical pearls, and treatment algorithms throughout to enhance clinical utility Directions for ""Future Research"" in each chapter highlight promising studies and new therapies Broad-based coverage of the full range of common sleep disorders and co-morbidities "

Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments New chapters...

In the past 25 years, the frontal lobes have dominated human neuroscience research. Functional neuroimaging studies have revealed their importance to brain networks involved in nearly every aspect of mental and cognitive functioning. Studies of patients with focal brain lesions have expanded on early case study evidence of behavioral, emotional, and cognitive changes associated with frontal lobe brain damage. The role of frontal lobe function and dysfunction in human development (in both children and older adults), psychiatric disorders, the dementias, and other brain diseases has also received rapidly increasing attention. In this useful text, 14 leading frontal lobe researchers review and synthesize the current state of knowledge on frontal lobe function, including structural and functional brain imaging, brain network analysis, aging and dementia, traumatic brain injury, rehabilitation, attention, memory, and consciousness. The book therefore provides a state-of-the-art account of research in this exciting area, and also highlights a number of new findings by some of the world's top researchers.

Social scientists have repeatedly uncovered a disturbing feature of economic inequality: people with larger incomes and better education tend to lead longer, healthier lives. This pattern holds across all ages and for virtually all measures of health, apparently indicating a biological dimension of inequality. But scholars have only begun to understand the complex mechanisms that drive this disparity. How exactly do financial well-being and human physiology interact? The Biological Consequences of Socioeconomic Inequalities incorporates insights from the social and biological sciences to quantify the biology of disadvantage and to assess how poverty gets under the skin to impact health. Drawing from unusually rich datasets of biomarkers, brain scans, and socioeconomic measures, Biological Consequences of Socioeconomic Inequalities illustrates exciting new paths to understanding social inequalities in health. Barbara Wolfe, William N. Evans and Nancy Adler begin the volume with a critical evaluation of the literature on income and health, providing a lucid review of the difficulties of establishing clear causal pathways between the two variables. In their chapter, Arun S....

An essential reference book for visual science.

This book describes the technical problems and solutions for automatically recognizing and parsing a medical image into multiple objects, structures, or anatomies. It gives all the key methods, including state-of- the-art approaches based on machine learning, for recognizing or detecting, parsing or segmenting, a cohort of anatomical structures from a medical image. Written by top experts in Medical Imaging, this book is ideal for university researchers and industry practitioners in medical imaging who want a complete reference on key methods, algorithms and applications in medical image recognition, segmentation and parsing of multiple objects. Learn: Research challenges and problems in medical image recognition, segmentation and parsing of multiple objects Methods and theories for medical image recognition, segmentation and parsing of multiple objects Efficient and effective machine learning solutions based on big datasets Selected applications of medical image parsing using proven algorithms Provides a comprehensive overview of state-of-the-art research on medical image recognition, segmentation, and parsing of multiple objects Presents efficient and effective approaches based...

This book constitutes the refereed proceedings of the 7th International Workshop on Machine Learning in Medical Imaging, MLMI 2016, held in conjunction with MICCAI 2016, in Athens, Greece, in October 2016. The 38 full papers presented in this volume were carefully reviewed and selected from 60 submissions. The main aim of this workshop is to help advance scientific research within the broad field of machine learning in medical imaging. The workshop focuses on major trends and challenges in this area, and presents works aimed to identify new cutting-edge techniques and their use in medical imaging.

Medical imaging is an important topic and plays a key role in robust diagnosis and patient care. It has experienced an explosive growth over the last few years due to imaging modalities such as X-rays, computed tomography (CT), magnetic resonance (MR) imaging, and ultrasound. This book focuses primarily on model-based segmentation techniques, which are applied to cardiac, brain, breast and microscopic cancer cell imaging. It includes contributions from authors working in industry and academia, and presents new material.

Deals with imaging of pathology of the visual system. This book is divided into two parts, general and special. In the general part, important basics of modern imaging methods are discussed. The knowledge on the indication, technique, and results of functional MR imaging is also presented.

Magnetoencephalography (MEG) is the only neuroimaging method that provides high spatial and temporal information of human brain activation. In addition, MEG is completely non-invasive and allows recordings with minimal preparation time. This makes it suitable to investigate even fetuses in utero. This volume in the International Review of Neurobiology series addresses the most relevant research areas and shows how MEG could be used for investigations over the whole life span in humans.

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