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Protecting Groups provides a critical survey of protecting group methodology and focuses on the most widely used protecting groups for the most common functional groups. Therefore it serves as an essential learning tool for advanced students and professionals in a broad range of disciplines involving organic synthesis. The book is organized by functional group and places special emphasis on deprotection conditions applied to complex structures where selectivity is a key issue. The discussion of each protecting group is divided into three sections beginning with deprotection conditions, followed by methods of formation, and ending with some characteristic NMR data to aid the reader in identifying the contribution from the protecting group. At the end of each chapter is a list of reviews for the topics covered in that chapter. // The content of this e-book was originally published in 2007.

The didactic presentation of the material makes this book an essential bench-top tool not only for specialists in organic chemistry, but also for students and all those involved in the preparation of organic molecules. Key Features: A critical survey of the most used protecting groups, as used by organic chemists Organization based on functional groups: hydroxyl ; diol; carbonyl; carboxyl; amine Special emphasis placed on deprotection conditions applied to complex structures where selectivity is a prime issue Transformations accompanied by key experimental details Examples from the recent literature span a wide domain of organic synthesis Over 500 schemes aid visual retrieval End-of-chapter list reviews which amplify topics covered.

Searching for reaction in organic synthesis has been made much easier in the current age of computer databases. However, the dilemma now is which procedure one selects among the ocean of choices. Especially for novices in the laboratory, it becomes a daunting task to decide what reaction conditions to experiment with first in order to have the best chance of success. This collection intends to serve as an "older and wiser lab-mate" one could have by compiling many of the most commonly used experimental procedures in organic synthesis. With chapters that cover such topics as functional group manipulations, oxidation, reduction, and carbon-carbon bond formation, Modern Organic Synthesis in the Laboratory will be useful for both graduate students and professors in organic chemistry and medicinal chemists in the pharmaceutical and agrochemical industries.

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This volume provides an authoritative and comprehensive coverage of the most recent advances in the production, synthesis, analysis and applications of isotopically labelled compounds. It focuses especially on areas of significant growth since the immediately preceding Seventh International Isotope Society Meeting held in Dresden, Germany in June 2000. Contributions are drawn from major research groups around the world, providing valuable information to research community with interests in the following areas: New methodologies in the production of isotopes Novel synthetic and biosynthetic approaches to isotopically labelled compounds Analysis of isotopically labeled compounds Application of isotopically labelled compounds in medical, agricultural, nutritional and environmental research and development Investigation and elucidation or organic and bioorganic mechanisms and pathways Regulatory and safety perspectives The next Symposium in this series will be held at Edinburgh, Scotland in the summer of 2006.

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